The best way to clear your clogged Main Drain Lines depends on the cause of the problem. Hydro jetting is a solution that’s best when clogs can’t be removed using a plumbing snake, such as heavy sludge and grease that has built up over time, or tree roots. Plumbing snakes are ideal for slow-draining lines or to remove occasional blockages, such as too much toilet paper or food stuck in your sink drain.